Vitamin C has many known relating to the protection of skurvi and flu. Fruits rich in vitamin C is
powerful antioxidants that can protect cellular DNA from oxidative damage. Serena Guarnieri and other researchers from the Division of Human Nutrition, University of Milan, Italy, suspected that vitamin C supplements do not have the same protective effect with fruits such as oranges. The test subject was given a glass of orange juice, drinks containing vitamin C, results processing and sugar solution. And drink orange juice with vitamin C that has been processed, each containing 150 mg of vitamin C while the sugar solution did not. Test subject's blood sample taken at 3 hours and 24 hours after drinking the test solution. The level of vitamin C in blood plasma menngkat after drinking orange juice and beverages containing vitamin C results processing.

DNA damage by oxidation decreased significantly in blood samples of the test subjects get a drink of orange juice as the vitamin C that has been processed and sugar solution showed no such protective effect. Thus, it can be concluded that vitamin C is not the only component responsible for the entioksidan effects, there are other things that need to be further investigated. Vitamin C is available in the matrix with various fruits and other beneficial substances kemungkina interact with each other. Other nutrition researchers suspected that the sugar in the juice may interact with vitamin C to produce antioxidant effect. Effects of phytochemical compounds (sianidin-3-glycosides, flavanon and carotenoids) are present in citrus need further investigation to clarify these allegations.